RELA gen Set
Dataset TRANSFAC Curated Transcription Factor Targets
Category genomics
Type transcription factor
Description v-rel avian reticuloendotheliosis viral oncogene homolog A|NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound khổng lồ either REL, RELA, or RELB. The most abundant size of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. (NCBI Entrez ren Database, 5970)
External Link http://www.ncbi.nlm.nih.gov/gene/5970
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Genes

344 target genes of the RELA transcription factor in low- or high-throughput transcription factor functional studies from the TRANSFAC Curated Transcription Factor Targets dataset.




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Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ABHD8 abhydrolase tên miền containing 8
ABI3 ABI family, thành viên 3
ACAN aggrecan
ACTN1 actinin, alpha 1
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADCK4 aarF tên miền containing kinase 4
ADGRB2 adhesion G protein-coupled receptor B2
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
AKT1S1 AKT1 substrate 1 (proline-rich)
ALG6 ALG6, alpha-1,3-glucosyltransferase
AMOTL1 angiomotin like 1
ANKFN1 ankyrin-repeat và fibronectin type III domain name containing 1
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGAP44 Rho GTPase activating protein 44
ARHGAP5 Rho GTPase activating protein 5
ARHGAP8 Rho GTPase activating protein 8
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ASCL3 achaete-scute family bHLH transcription factor 3
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATOH1 atonal homolog 1 (Drosophila)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BAZ2B bromodomain adjacent khổng lồ zinc finger domain, 2B
BCKDK branched chain ketoacid dehydrogenase kinase
BCL3 B-cell CLL/lymphoma 3
BCL6B B-cell CLL/lymphoma 6, thành viên B
BDNF brain-derived neurotrophic factor
BFSP1 beaded filament structural protein 1, filensin
BIRC3 baculoviral IAP repeat containing 3
BLCAP bladder cancer associated protein
BMF Bcl2 modifying factor
BMP2K BMP2 inducible kinase
BNC2 basonuclin 2
C16ORF47 chromosome 16 mở cửa reading frame 47
C19ORF68 chromosome 19 xuất hiện reading frame 68
C1QL1 complement component 1, q subcomponent-like 1
CACNG3 calcium channel, voltage-dependent, gamma subunit 3
CALCOCO1 calcium binding và coiled-coil domain name 1
CASKIN2 CASK interacting protein 2
CBX2 chromobox homolog 2
CCDC107 coiled-coil tên miền containing 107
CCL5 chemokine (C-C motif) ligand 5
CCM2L cerebral cavernous malformation 2-like
CD40 CD40 molecule, TNF receptor superfamily thành viên 5
CD69 CD69 molecule
CD70 CD70 molecule
CD83 CD83 molecule
CD86 CD86 molecule
CDC14A cell division cycle 14A
CDC42SE1 CDC42 small effector 1
CDK6 cyclin-dependent kinase 6
CFAP69 cilia và flagella associated protein 69
CHD4 chromodomain helicase DNA binding protein 4
CLCN1 chloride channel, voltage-sensitive 1
CLCN2 chloride channel, voltage-sensitive 2
CLDN5 claudin 5
CLOCK clock circadian regulator
COL11A2 collagen, type XI, alpha 2
COL16A1 collagen, type XVI, alpha 1
CPD carboxypeptidase D
CREB1 cAMP responsive element binding protein 1
CSF1R colony stimulating factor 1 receptor
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTAGE4 CTAGE family, member 4
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
CTGF connective tissue growth factor
CUEDC1 CUE domain containing 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR5 chemokine (C-X-C motif) receptor 5
CXORF21 chromosome X mở cửa reading frame 21
CYB5A cytochrome b5 type A (microsomal)
CYLD cylindromatosis (turban tumor syndrome)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DAP3 death associated protein 3
DCLK1 doublecortin-like kinase 1
DDR1 discoidin domain name receptor tyrosine kinase 1
DOCK4 dedicator of cytokinesis 4
DSC2 desmocollin 2
E2F3 E2F transcription factor 3
EBF1 early B-cell factor 1
EBI3 Epstein-Barr virut induced 3
EDN2 endothelin 2
EGF epidermal growth factor
EHF ets homologous factor
EIF4A2 eukaryotic translation initiation factor 4A2
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF5A eukaryotic translation initiation factor 5A
ELMSAN1 ELM2 & Myb/SANT-like tên miền containing 1
ENO3 enolase 3 (beta, muscle)
ERN1 endoplasmic reticulum to nucleus signaling 1
ETV6 ets variant 6
FAM129A family with sequence similarity 129, member A
FAM43B family with sequence similarity 43, member B
FBXL12 F-box và leucine-rich repeat protein 12
FGF1 fibroblast growth factor 1 (acidic)
FGF12 fibroblast growth factor 12
FGF17 fibroblast growth factor 17
FLOT1 flotillin 1
FLRT1 fibronectin leucine rich transmembrane protein 1
FOXJ2 forkhead box J2
FOXS1 forkhead box S1
FTHL17 ferritin, heavy polypeptide-like 17
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GADD45B growth arrest and DNA-damage-inducible, beta
GATA4 GATA binding protein 4
GDPD5 glycerophosphodiester phosphodiesterase domain name containing 5
GEN1 GEN1 Holliday junction 5' flap endonuclease
GGNBP2 gametogenetin binding protein 2
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
GPBP1 GC-rich promoter binding protein 1
GPHN gephyrin
GPM6A glycoprotein M6A
GREM1 gremlin 1, DAN family BMP antagonist
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2 chiều
GRK5 G protein-coupled receptor kinase 5
HCFC1 host cell factor C1
HCST hematopoietic cell signal transducer
HIVEP1 sida type I enhancer binding protein 1
HNRNPR heterogeneous nuclear ribonucleoprotein R
HOXA11 homeobox A11
HOXB9 homeobox B9
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- & steroid delta-isomerase 7
HSP90B1 heat shock protein 90kDa beta (Grp94), thành viên 1
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
ICAM1 intercellular adhesion molecule 1
IER3 immediate early response 3
IER5 immediate early response 5
IFNB1 interferon, beta 1, fibroblast
IGDCC3 immunoglobulin superfamily, DCC subclass, thành viên 3
IL13 interleukin 13
IL17C interleukin 17C
IL1A interleukin 1, alpha
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
IL1RN interleukin 1 receptor antagonist
IL23A interleukin 23, alpha subunit p19
IL27 interleukin 27
IL27RA interleukin 27 receptor, alpha
IL2RA interleukin 2 receptor, alpha
IL4I1 interleukin 4 induced 1
IL6ST interleukin 6 signal transducer
ILK integrin-linked kinase
INO80D INO80 complex subunit D
IRF1 interferon regulatory factor 1
ITGB4 integrin, beta 4
ITPKC inositol-trisphosphate 3-kinase C
JAK3 Janus kinase 3
JARID2 jumonji, AT rich interactive tên miền 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KAT7 K(lysine) acetyltransferase 7
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, thành viên 2
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KCNT2 potassium channel, sodium activated subfamily T, thành viên 2
KLK9 kallikrein-related peptidase 9
KRT23 keratin 23, type I
KRT36 keratin 36, type I
KRTAP13-1 keratin associated protein 13-1
KY kyphoscoliosis peptidase
LAMA1 laminin, alpha 1
LIG1 ligase I, DNA, ATP-dependent
LIX1L Lix1 homolog (chicken) like
LRCH1 leucine-rich repeats and calponin homology (CH) domain name containing 1
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAG myelin associated glycoprotein
MAML2 mastermind-like 2 (Drosophila)
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPK6 mitogen-activated protein kinase 6
MED1 mediator complex subunit 1
MIA melanoma inhibitory activity
MIR17HG miR-17-92 cluster host ren
MITF microphthalmia-associated transcription factor
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
MMP9 matrix metallopeptidase 9
MOB3C MOB kinase activator 3C
MSC musculin
MSN moesin
MSX1 msh homeobox 1
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFKB2 nuclear factor of kappa light polypeptide gen enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NIPBL Nipped-B homolog (Drosophila)
NLK nemo-like kinase
NOD2 nucleotide-binding oligomerization domain containing 2
NOL4 nucleolar protein 4
NR2F2 nuclear receptor subfamily 2, group F, thành viên 2
NTN1 netrin 1
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2
NXPH4 neurexophilin 4
OPCML opioid binding protein/cell adhesion molecule-like
ORAI1 ORAI calcium release-activated calcium modulator 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PARP8 poly (ADP-ribose) polymerase family, thành viên 8
PCBP4 poly(rC) binding protein 4
PCDH10 protocadherin 10
PCDH12 protocadherin 12
PCSK2 proprotein convertase subtilisin/kexin type 2
PFN1 profilin 1
PLAU plasminogen activator, urokinase
PLXNB1 plexin B1
PNKD paroxysmal nonkinesigenic dyskinesia
POU2F3 POU class 2 homeobox 3
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRDM12 PR domain containing 12
PRX periaxin
PTGES prostaglandin E synthase
PTHLH parathyroid hormone-like hormone
PTMS parathymosin
PURG purine-rich element binding protein G
RALGDS ral guanine nucleotide dissociation stimulator
RANBP10 RAN binding protein 10
RAP2C RAP2C, thành viên of RAS oncogene family
RASGRP4 RAS guanyl releasing protein 4
RASSF2 Ras association (RalGDS/AF-6) tên miền family member 2
RBMS1 RNA binding motif, single stranded interacting protein 1
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RIMS2 regulating synaptic membrane exocytosis 2
RIN2 Ras and Rab interactor 2
RND1 Rho family GTPase 1
RNF43 ring finger protein 43
RPS19 ribosomal protein S19
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRAS related RAS viral (r-ras) oncogene homolog
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RSF1 remodeling & spacing factor 1
S1PR2 sphingosine-1-phosphate receptor 2
SALL1 spalt-like transcription factor 1
SAMSN1 SAM domain, SH3 domain và nuclear localization signals 1
SDC4 syndecan 4
SEC14L2 SEC14-like 2 (S. Cerevisiae)
SEC63 SEC63 homolog (S. Cerevisiae)
SESN2 sestrin 2
SH2B3 SH2B adaptor protein 3
SHOX2 short stature homeobox 2
SIN3A SIN3 transcription regulator family thành viên A
SIRT2 sirtuin 2
SIX4 SIX homeobox 4
SIX5 SIX homeobox 5
SLAMF8 SLAM family thành viên 8
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), thành viên 2
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), thành viên 2
SLC16A6 solute carrier family 16, member 6
SLC44A1 solute carrier family 44 (choline transporter), thành viên 1
SLC6A12 solute carrier family 6 (neurotransmitter transporter), thành viên 12
SMC6 structural maintenance of chromosomes 6
SMOC1 SPARC related modular calcium binding 1
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SOBP sine oculis binding protein homolog (Drosophila)
SOX10 SRY (sex determining region Y)-box 10
SOX3 SRY (sex determining region Y)-box 3
SOX5 SRY (sex determining region Y)-box 5
SP6 Sp6 transcription factor
SPTB spectrin, beta, erythrocytic
STAT6 signal transducer và activator of transcription 6, interleukin-4 induced
STC2 stanniocalcin 2
STON2 stonin 2
STX19 syntaxin 19
STX4 syntaxin 4
SUCO SUN tên miền containing ossification factor
SUN2 Sad1 & UNC84 domain containing 2
TAL1 T-cell acute lymphocytic leukemia 1
TATDN1 TatD DNase domain containing 1
TAZ tafazzin
TBC1D17 TBC1 domain family, thành viên 17
TCEA2 transcription elongation factor A (SII), 2
TFE3 transcription factor binding lớn IGHM enhancer 3
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TIFA TRAF-interacting protein with forkhead-associated domain
TJAP1 tight junction associated protein 1 (peripheral)
TLX1 T-cell leukemia homeobox 1
TLX3 T-cell leukemia homeobox 3
TNF tumor necrosis factor
TNFRSF1B tumor necrosis factor receptor superfamily, thành viên 1B
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNIP1 TNFAIP3 interacting protein 1
TP53 tumor protein p53
TP63 tumor protein p63
TRAF4 TNF receptor-associated factor 4
TRIB2 tribbles pseudokinase 2
TRIM47 tripartite motif containing 47
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TSEN54 TSEN54 tRNA splicing endonuclease subunit
TSLP thymic stromal lymphopoietin
TSNAXIP1 translin-associated factor X interacting protein 1
TSPEAR thrombospondin-type laminin G domain & EAR repeats
TUBGCP4 tubulin, gamma complex associated protein 4
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UACA uveal autoantigen with coiled-coil domains & ankyrin repeats
UBD ubiquitin D
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2H ubiquitin-conjugating enzyme E2H
UBE2I ubiquitin-conjugating enzyme E2I
UBE4B ubiquitination factor E4B
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
VCAM1 vascular cell adhesion molecule 1
VEZF1 vascular endothelial zinc finger 1
VSX2 visual system homeobox 2
WNT10A wingless-type MMTV integration site family, member 10A
WNT10B wingless-type MMTV integration site family, thành viên 10B
WNT4 wingless-type MMTV integration site family, member 4
WRAP53 WD repeat containing, antisense to TP53
WRN Werner syndrome, RecQ helicase-like
XKR8 XK, Kell blood group complex subunit-related family, thành viên 8
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
YY1AP1 YY1 associated protein 1
ZBTB11 zinc finger & BTB domain name containing 11
ZBTB5 zinc finger & BTB tên miền containing 5
ZBTB9 zinc finger & BTB domain containing 9
ZDHHC8 zinc finger, DHHC-type containing 8
ZEB1 zinc finger E-box binding homeobox 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZIC4 Zic family member 4
ZMYND15 zinc finger, MYND-type containing 15
ZNF232 zinc finger protein 232
ZSCAN29 zinc finger & SCAN domain containing 29